Products related to Disease:
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Heart Development and Disease : Volume 156
Heart Development and Disease, Volume 156 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters including Macrophages during heart valve development, Computational models of cardiovascular biology, Mechanisms of early sarcomere assembly, Role of RNA binding proteins during heart development and disease, Early heart development and morphogenesis, PSC models for development and disease, ECM or SHF development, Role of metabolism during heart development, Cellular ploidy in cardiac biology, and Genetics of CHD in the human population.
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Public Health, Disease and Development in Africa
The closure of the Millennium Development Goals (MDGs) in 2015 prompted the need for a book of this kind.An interdisciplinary group of global health scholars contribute to the understanding of the emerging and fast-growing problem of the dual burden of communicable and non-communicable diseases (NCDs) in Africa.This book is timely, as the international community has moved from the MDGs to adopt the Sustainable Development Goals (SDGs) as the blueprint for a new human development agenda.Contributions and case studies are situated in the revised Epidemiologic and Nutrition Transition Model to capture the current situation, referencing communicable and NCDs on the African continent.The case studies encapsulated aim to help minimize negative health outcomes and improve population health, well-being, and equity in the future. This book will be significant in policy circles to assist international organizations, governments, and United Nations agencies.It aims to chart the future for health in Africa in light of recently adopted SDGs.This book is also a useful complementary reader for global public health related courses.
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Cell Migration in Development, Health and Disease
This textbook gives an insight into the importance of cell migration in health during development, wound healing and immune responses as well as in disease with particular focus on cancer.The reader will learn about the different ways cells migrate to allow cellular changes during development to occur, as well as responses to injury and threat by foreign invaders.Cell migration is a driver of invasion and ultimately metastasis in cancer and as such we will give examples from highly aggressive cancer such as brain tumours.The book also includes an introduction to mathematical modelling to predict cell migration, information on the development of software for analysis of data generated in 2D and 3D as well as recent developments in the investigations into cell migration using 3D bioprinting. This textbook will be a great learning tool for advanced undergraduate students and Master students with the relevant science degrees such as in cell biology, developmental biology, cancer research, and tumour biology.
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Innovative Methods for Rare Disease Drug Development
In the United States, a rare disease is defined by the Orphan Drug Act as a disorder or condition that affects fewer than 200,000 persons.For the approval of "orphan" drug products for rare diseases, the traditional approach of power analysis for sample size calculation is not feasible because there are only limited number of subjects available for clinical trials.In this case, innovative approaches are needed for providing substantial evidence meeting the same standards for statistical assurance as drugs used to treat common conditions.Innovative Methods for Rare Disease Drug Development focuses on biostatistical applications in terms of design and analysis in pharmaceutical research and development from both regulatory and scientific (statistical) perspectives.Key Features: Reviews critical issues (e.g., endpoint/margin selection, sample size requirements, and complex innovative design). Provides better understanding of statistical concepts and methods which may be used in regulatory review and approval. Clarifies controversial statistical issues in regulatory review and approval accurately and reliably. Makes recommendations to evaluate rare diseases regulatory submissions. Proposes innovative study designs and statistical methods for rare diseases drug development, including n-of-1 trial design, adaptive trial design, and master protocols like platform trials. Provides insight regarding current regulatory guidance on rare diseases drug development like gene therapy.
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Which disease is known as maple disease?
Maple disease is a term used to describe a condition called maple syrup urine disease (MSUD). This is a rare genetic disorder that affects the body's ability to break down certain amino acids, leading to a buildup of these substances in the blood and urine. The condition gets its name from the distinctive sweet smell of the affected individual's urine, which is similar to that of maple syrup. If left untreated, MSUD can lead to serious health complications, including neurological problems and developmental delays.
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What is the disease Fish Disease 2?
Fish Disease 2, also known as Columnaris disease, is a bacterial infection that affects freshwater fish. It is caused by the bacteria Flavobacterium columnare and can result in symptoms such as white or grayish patches on the skin, frayed fins, and lethargy. The disease is highly contagious and can spread rapidly through a fish population. It is important to promptly diagnose and treat Fish Disease 2 to prevent widespread infection and mortality in aquariums or fish farms.
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Which disease is referred to as maple disease?
Maple disease refers to a condition known as maple syrup urine disease (MSUD). This is a rare genetic disorder that affects the body's ability to break down certain amino acids, leading to a buildup of toxic substances in the blood and urine. The name "maple syrup urine disease" comes from the distinctive sweet smell of the urine in affected individuals. If left untreated, MSUD can cause serious health problems, including neurological damage and developmental delays.
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Is caries an infectious disease or a lifestyle disease?
Caries, also known as tooth decay or cavities, is primarily considered an infectious disease. It is caused by bacteria in the mouth, particularly Streptococcus mutans, which produce acids that erode the tooth enamel. However, lifestyle factors such as poor oral hygiene, high sugar consumption, and lack of regular dental care can contribute to the development and progression of caries. Therefore, while caries is fundamentally an infectious disease, lifestyle choices can play a significant role in its occurrence.
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Retinoids in Development and Disease : Volume 161
Retinoids in Development and Disease, Volume 161 in the Current Topics in Developmental Biology series focuses on the role of retinoids during development and disease.Topics covered include Retinoids, Retinol-Binding Protein 2 (RBP2), Retinol-Binding Protein 4 (RBP4): Obesity and Metabolic Disease, Early Retinoic Acid Signaling Organizes the Body Axis and Defines Domains for the Forelimb and Eye, Rethinking Retinoic Acid Self-Regulation: A Signaling Robustness Network Approach, Meiotic initiation in the fetal ovary without retinoic acid receptors: an unforeseen twist, Action of retinoic acid on progenitor cells in the testis, amongst many other topics. Additional sections cover Retinoic acid homeostasis and disease, Redefining the roles of endogenously produced retinoic acid in heart development and regeneration: lessons from genetic models, The Multifaceted Roles of Retinoids in Vision, Eye Development, and Retinal Degenerative Diseases, Essential roles for retinoid signaling in craniofacial development, and much more.
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Disease
History will never seem boring again once you have read all these fascinating stories about events that happened in the past.Illustrations from the past as well as pictures of actual items involved in some of history's most famous stories.|History will never seem boring again once you have read all these fascinating stories about events that happened in the past.Illustrations from the past as well as pictures of actual items involved in some of history's most famous stories.
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Disease!
History will never seem boring again once you have read all these fascinating stories about events that happened in the past.Illustrations from the past as well as pictures of actual items involved in some of history's most famous stories.|History will never seem boring again once you have read all these fascinating stories about events that happened in the past.Illustrations from the past as well as pictures of actual items involved in some of history's most famous stories.
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Disease
In 1942 life expectancy at birth was 66 for women and 60 for men.Death was usually due to degenerative and infectious diseases.The greatest postwar success in the fight against disease was the establishment of the NHS and care that was free at the point of delivery.Life expectancy rose dramatically, but since 2011 incremental improvements have stalled and even, in some regions, begun to reverse.Infant mortality rates have crept up and the postcode lottery of health provision underscores the level of social inequality in the UK. Good health is not simply the absence of disease.It is the collective of physical, social and mental well-being.It is the product of nutrition and genetics, of healthy lifestyles and preventative health interventions.It is the interaction between the conditions in which we live, work, play and age.Yet access to many of the things that make and keep us healthy are not evenly distributed in the population.Achieving good health is then deeply entwined with all aspects of society and cannot simply be solved by policies in one area alone. In our rediscovery of Beveridge, the shadow of the pandemic looms large.It is has never been more urgent to address the underlying causes of Disease. And it has never been clearer that these determinants are not only social or physiological, but also political.
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Which disease is known as maple syrup urine disease?
Maple syrup urine disease is a rare genetic disorder that is characterized by a distinctive sweet odor of the urine, similar to that of maple syrup. This disease is caused by a deficiency in certain enzymes that are needed to break down certain amino acids. If left untreated, maple syrup urine disease can lead to serious health complications, including neurological problems and developmental delays. Early diagnosis and management of this condition are crucial to prevent these complications.
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What is a neurodegenerative disease, such as Alzheimer's disease?
A neurodegenerative disease is a condition that primarily affects the neurons in the brain, leading to progressive degeneration and ultimately, the death of these cells. Alzheimer's disease is a specific type of neurodegenerative disease characterized by memory loss, cognitive decline, and changes in behavior. It is the most common cause of dementia and is believed to be caused by a combination of genetic, environmental, and lifestyle factors. Currently, there is no cure for Alzheimer's disease, and treatment focuses on managing symptoms and improving quality of life.
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Which disease does Dave Gahan refer to in "Shake the Disease"?
In the song "Shake the Disease," Dave Gahan refers to the disease of addiction. The lyrics describe the struggle of trying to break free from the hold that addiction has on a person's life. Gahan sings about the desire to overcome this disease and find a way to move forward. The song's message is one of hope and determination in the face of personal challenges.
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Is circulatory disorder a disease or a symptom of another disease?
Circulatory disorder can be both a disease and a symptom of another disease. Circulatory disorders such as hypertension, atherosclerosis, and peripheral artery disease can be considered diseases in themselves, as they involve dysfunction of the circulatory system. However, circulatory disorders can also be symptoms of other underlying conditions, such as heart disease, diabetes, or autoimmune disorders. In these cases, the circulatory disorder is a manifestation of the primary disease and may require treatment of the underlying condition to effectively manage the circulatory symptoms.
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